The reference site for Cefamandole

Cefamandole (INN, also known as cephamandole) is a second-generation broad-spectrum cephalosporin antibiotic.

WHAT IS Cefamandole?

Cefamandole belongs to a group of drugs called cephalosporins. These are antibiotics and work by killing or stopping the growth of bacteria (germs) which are causing the infection.

This medicine is used to treat infections such as lower respiratory tract infections, pneumonia, pulmonary complications resulting from cystic fibrosis, urinary tract infections, septicemia, soft tissue and post surgical infections, peritonitis, cellulites, abscesses, wound infections, and bone and joint infections.

 

Brand Name(s): Mandol
CAS nº: 34444-01-4
(sef a man’ dole)

 

Product Info

The sections below will provide you with more specific information and guidelines related to cefamandole and its correct use. Please read them carefully.

FDA Information

Cefamandole has been approved by the US Food and Drug Administration. However, a prescription is required for this medicine.

Please visit the official site of the FDA for further information.

Why is this medication prescribed?

Cefamandole belongs to a group of drugs called cephalosporins. These are antibiotics and work by killing or stopping the growth of bacteria (germs) which are causing the infection.

This medicine is used to treat infections such as lower respiratory tract infections, pneumonia, pulmonary complications resulting from cystic fibrosis, urinary tract infections, septicemia, soft tissue and post surgical infections, peritonitis, cellulites, abscesses, wound infections, and bone and joint infections.

Other uses for this medicine

This medication has not been approved for any alternative uses other than those mentioned in the product information section.

Dosage and using this medicine

Cefamandole nafate is given as an injection in a vein over 15 to 30 minutes, or as an injection into the muscle.

The dose depends upon the type of infection and whether you have any problems with your kidneys. The dose is given every 6 to 8 hours.

Before you administer cefamandole, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks.

It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason because your infection could worsen and result in hospitalization. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

What special precautions should I follow?

BEFORE TAKING CEFAMANDOLE:

Please inform your doctor and pharmacist if you are allergic to cefamandole, any other cephalosporin [e.g., cefaclor (Ceclor®), cefadroxil (Duricef®), or cephalexin (Keflex®)], penicillins, or any other drugs.

Always tell your doctor and pharmacist what prescription and non-prescription medications you are taking, especially other antibiotics, probenecid (Benemid®), and vitamins.

Tell your doctor if you have or have ever had kidney, liver, or gastrointestinal disease (especially colitis).

Furthermore, let your doctor know as soon as possible if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cefamandole, call your doctor.

Additionally, you should avoid alcohol completely while receiving cefamandole and for 3 days after receiving cefamandole. Any alcoholic beverage can cause a sudden reaction, with an upset stomach, vomiting, flushing, sweating, headache, and rapid heartbeat. This warning also applies to alcohol-containing medications such as cough syrups and elixirs. Talk to your pharmacist or physician before taking any new medication.

If you have diabetes and regularly check your urine for sugar, use Clinistix® or TesTape®. Do not use Clinitest® tablets because cefamandole may cause false positive results.

What should I do if I forget a dose?

Cefamandole needs to be given on a regular schedule. Take the missed dose as soon as you remember and then take the rest of the doses for the day at regularly spaced time intervals.

If you miss more than one dose, call your doctor for instructions.

What side effects can this medication cause?

Although side effects from cefamandole are not common, they can occur. You should be aware of the symptoms of infection in case your infection worsens or a new infection develops.

If you notice any of the following symptoms, tell your health care provider as soon as possible:

fever
unusual tiredness or weakness
chills
shaking
nighttime sweating
loss of appetite

If you are receiving cefamandole in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin).

If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:

tenderness
warmth
irritation
drainage
redness
swelling
pain

What storage conditions are needed for this medicine?

Your health care provider probably will give you several days supply of cefamandole at a time. If you are receiving cefamandole intravenously (in your vein), you probably will be told to store it in the refrigerator or freezer.

Take your next dose from the refrigerator 1 hour before using it, and place it in a clean, dry area to allow it to warm to room temperature.

If you are told to store additional cefamandole in the freezer, always move a 24 hour supply to the refrigerator for the next day’s use.

Do not refreeze medications.

In case of an emergency/overdose

In the case of an overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, please call the local emergency services on 911.

Product Images

PICTURES OF CEFAMANDOLE PILLS

Below you will find images and specific information on the principal types of cefamandole that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

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